Caenorhabditis elegans Tracking


Main Window of WormTracker

Result of WormTracker

Mobility of a slow Worm
Mobility slow Worm

Mobility of a fast Worm
Mobility fast Worm


Wissenschaftlichen Anwendungen des WormTrackers:

9) Schlotterer A, Pfisterer F, Kukudov G, Heckmann B, Henriquez D, Morath C, Krämer BK, Hammes HP, Schwenger V, Morcos M.
Neuronal damage and shortening of lifespan in C. elegans by peritoneal dialysis fluid: Protection by glyoxalase-1.
Biomed Rep. 2018;8(6):540-6.

8) Riedinger C, Mendler M, Schlotterer A, Fleming T, Okun J, Hammes HP, Herzig S, Nawroth PP.
High-glucose toxicity is mediated by AICAR-transformylase/IMP cyclohydrolase and mitigated by AMP-activated protein kinase in Caenorhabditis elegans.
J Biol Chem. 2018;293(13):4845-59.

7) Mendler M, Riedinger C, Schlotterer A, Volk N, Fleming T, Herzig S, Nawroth PP, Morcos M.
Reduction in ins-7 gene expression in non-neuronal cells of high glucose exposed Caenorhabditis elegans protects from reactive metabolites, preserves neuronal structure and head
motility, and prolongs lifespan.

J Diabetes Complications. 2017;31(2):304-10.

6) Schlotterer A, Greten HJ, Remppis BA, Kukudov G, Efferth T, Machado J, Humpert P, Hammes HP, Morcos M.
Neuroprotection and antioxidative effects of Sijunzi Tang Decoction in the nematode Caenorhabditis elegans.
Eur J Integr Med. 2016;8(4):526-32.

5) Wongchai K, Schlotterer A, Lin J, Humpert PM, Klein T, Hammes HP, Morcos M.
Protective Effects of Liraglutide and Linagliptin in C. elegans as a New Model for Glucose-Induced Neurodegeneration.
Horm Metab Res. 2016;48(1):70-5.

4) Mendler M, Schlotterer A, Ibrahim Y, Kukudov G, Fleming T, Bierhaus A, Riedinger C, Schwenger V, Herzig S, Hecker M, Tyedmers J, Nawroth PP, Morcos M.
daf-16/FOXO and glod-4/glyoxalase-1 are required for the life-prolonging effect of human insulin under high glucose conditions in Caenorhabditis elegans.
Diabetologia. 2015;58(2):393-401.

3) Schlotterer A, Hamann A, Kukudov G, Ibrahim Y, Bozorgmehr F, Humpert P, Bierhaus A, Nawroth PP, Morcos M.
Repression des mitochondrialen DNA-Reparatursystems schädigt das neuronale System und verkürzt die Lebensspanne von C. elegans.
Diabetologie und Stoffwechsel. 2008; 3: S66.

2) Ibrahim Y, Schlotterer A, Kukudov G, Humpert P, Rudofsky G, Tafel J, Hamann A, Bierhaus A, Nawroth PP, Morcos M.
Effects of normal human insulin, insulin aspart, and insulin detemir on the lifespan of Caenorhabditis elegans.
Diabetologie und Stoffwechsel. 2008; 3.

1) Schlotterer A, Hamann A, Kukudov G, Ibrahim Y, Heckmann B, Bozorgmehr F, Pfeiffer M, Hutter H, Stern D, Du X, Brownlee M, Bierhaus A, Nawroth P, Morcos M.
Apurinic/apyrimidinic endonuclease 1, p53, and thioredoxin are linked in control of aging in C. elegans.
Aging Cell. 2010 Jun;9(3):420-32.

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